Protease 4.5 on the European supplement market
Most ingredient pages tell you what Protease 4.5 is. This one shows how the European supplement market actually uses it — who sells it, who advertises it, and at what price.
RavenBI Market Intelligence · measured 25 Oct 2026 · observed, not estimated. Ad counts are active creatives in Meta's public Ad Library; product and price data come from public listings across the EU and US. Figures change weekly.
RavenBI tracks 289 Protease 4.5 products from 173 brands across the EU and US. 6 brands advertise it on Meta right now, and new-ad activity held roughly steady in the last 30 days. France shows the heaviest advertising, while United Kingdom has the largest shelf. The median EU shelf price sits around €29.
New Protease 4.5 ads launched per month on Meta — last 6 months.
How brands use Protease 4.5, market by market
Products and brands that sell it, active ads and brands that advertise it, and the median shelf price — per market.
| Market | Products | Brands selling | Active ads | Brands advertising | Median price |
|---|---|---|---|---|---|
| Germany | 27 | 18 | — | — | €38.90 |
| United Kingdom | 93 | 43 | 2 | 2 | £32.95 |
| France | 9 | 9 | 7 | 2 | €25.95 |
| Italy | 16 | 13 | — | — | €24.90 |
| Spain | 29 | 12 | 2 | 1 | €24.93 |
| Romania | 39 | 24 | — | — | 67.00 RON |
| United States | 38 | 29 | 1 | 1 | $38.00 |
| Austria | 5 | 3 | — | — | — |
Who is on the shelf right now
Top brands by number of Protease 4.5 products, and the forms they use.
Most-used forms
| Form | Products |
|---|---|
| Protează | 241 |
| Protează 4.5 (4.5) | 38 |
| Protează 4.5 (A. oryzae) | 3 |
| Protează 4.5 (fungal source) | 2 |
| Protease 4.5 Type II | 2 |
| Protează 4.5 (SP) | 2 |
Regulatory & positioning
| Botanical source | Protease 4.5 |
|---|---|
| Novel food status | — |
| EFSA authorized health claims | refused |
| Marketed categories (observed) | gut health, energy |
Where Protease 4.5 shows up
Across the ad channels and marketplaces RavenBI tracks.
See the ads, listings and shops behind these numbers →
What is Protease 4.5?
Protease 4.5 is an enzyme classified as a proteolytic enzyme, which functions by breaking down proteins into smaller peptides and amino acids. It is commonly included in dietary supplements formulated for digestive support and gut health, as well as in products marketed for energy and overall wellness. Protease enzymes like Protease 4.5 are often combined with other enzymes or digestive aids to enhance protein digestion and nutrient absorption in various supplement formulations.
This overview was generated with AI from public information and RavenBI's classification. Informational only, not medical advice.
30,000+ ingredients tracked across the EU + US · Live competitor ads, prices and product claims · Spot under-served demand in each market before rivals do.
Start free trial — full access